It has been suggested that DNA methylation can work in concert with other epigenetic factors. leading to changes in cellular phenotypes. For example. DNA demethylation modifications producing 5-hydroxymethylcytosine (5hmC) are thought to interact with histone modifications to influence the acquisition of embryonic stem cell (ESC) potency. https://jalyttlers.shop/product-category/loaf-tin/
A hypothetical trivalent epigenetic code that affects the nature of human ESCs.
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