During The absence of the enzyme, as in Crigler-Najjar syndrome style I, the amounts of unconjugated bilirubin will increase, resulting in jaundice. Unconjugated bilirubin is water-insoluble, and substantial degrees can deposit during the brain bringing about a condition known as kernicterus. Serious hyperbilirubinemia typically develops in the initial several times https://www.youtube.com/shorts/IuPMi7CvqAo